The durability of vaccine protection is another key area that requires a better understanding of the fundamentals of immune memory, a key question being how can we limit the acute contraction of the adaptive immune response after prophylactic vaccination and limit attrition of long-term memory , in particular for nAb titers in the blood?
This dual mechanism of action supports both acute and long-term cellular protection strategies
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Philadelphia, PA: Lippincott Williams and Wilkins (2005)
Here are some times to consider changing the dose: If treatment isnt working well, increase the dose or how often its given If B12 levels are too high, lower the dose Change the dose if the patients health changes or new issues come up By sticking to these guidelines, doctors can make B12 treatment better for each patient