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Many users have reported improvements in their emotional and psychological well-being

Reference: Ndumele CE, Rodriguez F, Dixon DL, et al

The biggest change is that the decision is no longer based on an automatic rule, like stopping your medication for a week

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A 2017 paper in Drug Testing and Analysis compiled the structure-activity relationship for peptidic growth-hormone secretagogues including ipamorelin, NN703, and related analogues (PMID 26811125)