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168 Oxidative modifications, such as nitrosylation at Cys93 and Cys310, influence subcellular localization
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SNIP1 and SF3B1 are important players in neurogenesis 43,46,49,114 and defects in other spliceosome activation proteins, such as PQBP1 115 , are known to cause neurological disorders
However, it is important to acknowledge that uricosuric agents and emerging therapies that increase renal clearance of uric acid may also raise the risk of renal adverse events
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