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Notably, nutraceuticals like RSV, PPR, and QUE have been shown to inhibit CYP3A4 activity, thereby reducing systemic drug elimination rates and increasing toxicity risks due to prolonged drug retention in circulation (9, 21, 32, 54)

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Elevated IgE antibody levels were noted in around of 80% AD patients, and IgE specific for common inhalant and food allergens were also detected in most patients (144)

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