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FDA banned it in late 2023 "Category 2: Substance with Safety Concerns" Why the FDA banned it: Potential immune reactions (immunogenicity) Manufacturing impurities in compounded versions Complete lack of human safety data Risk of contamination Legal status: NOT FDA-approved Illegal to compound in pharmacies Banned by WADA for athletes Possession not illegal (it's not a DEA scheduled substance) Sold online as "research chemical" 2

& Bhushan, A

Kawase, A

(A ) PLS-DA score plot as multivariate data analyses based on metabolomics data between three tamoxifen-treated groups (each group contains 9 samples) compared to the control group (n = 9)

doi:10.1172/jci.insight.146334