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___ Special thanks to the Terasaki Institute and Matterworks for their support and collaboration towards this project

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(3) Lack of Early Indicators- prior to the cardiovascular outcomes trials (CVOTs), there was no strong evidence or clear biological indicators suggesting that this class of drug would have a direct effect on cardiovascular health

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Both acute and chronic alcohol consumption can increase ROS production and lead to oxidative stress

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doi:10.3390/ijms21228765 11

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