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These types of inhibitors, with respect of their mode of actions, can be divided into two categories: those blocking a single virulence factor and those blocking global bacterial processes involved in pathogen virulence, such as the two-component system, the quorum sensing system, secretion systems, or post-translational protein modifications (Duncan et al
Stabilization of the catalytic thiolate in a mammalian glutaredoxin: structure, dynamics and electrostatics of reduced pig glutaredoxin and its mutants
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