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A key challenge in studying native GLP-1 is its extremely short in vivo half-life of approximately 12 minutes, owing to rapid inactivation by dipeptidyl peptidase-4 (DPP-4), which cleaves the N-terminal His-Ala dipeptide from GLP-1 to produce the inactive metabolite GLP-1(936)amide

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For more gentle meal ideas when appetite is tiny or nausea is hovering, these guides fit naturally here: What to Eat When Nauseous and Eating on GLP-1: What to Eat for Tiny Appetite + Nausea