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7779 Furthermore, a recent report demonstrated that exogenous GSH at physiological concentration (10 mM) enhanced susceptibility to chloramphenicol, novobiocin, and tetracycline, while decreasing susceptibility to ciprofloxacin, erythromycin, and kanamycin in A

The most well-established among them appears to be nuclear factor erythroid 2-related factor 2 (Nrf2), which is likely activated by redox status changes of the kelch-like ECH associated protein 1 (Keap1) induced by NAPQI

This per-tim complex accumulates in the cytoplasm before entering the nucleus to inhibit its own transcription by repressing the transcriptional activators Clock (Clk) and cycle (cyc) (Lee et al., 1999

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Mercury causes severe brain abnormalities, for example in Minamata disease