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Alpha-synuclein aggregation in Parkinsons disease

A large-scale whole-genome meta-analysis of serious autoimmune T2DM (research object = 452, control = 2,744) and focal epilepsy (research object = 929, control = 212,532) in Europeans revealed that genetic susceptibility to severe autoimmune T2DM was associated with an increased risk of focal epilepsy (83)

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During mastication they are enzimatically converted into thiocyanates, goitrin metabolites, that cause a competitive inhibition of the sodium/iodide symporter, thus inhibiting the thyroid hormones synthesis and possibly causing hypothyroidism [156]

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