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CON maintained the initial level until the end of the study, while CAR decreased to the minimum at 24 h and subsequently reached the baseline level by the end of the experiment

Reto, M., Figueira, M

And here is a detail that gets overlooked constantly: participants who received an initial starting dose of 4 mg experienced more GI symptoms than those who started at 2 mg

In addition, carnitine also depletes mitochondrial and ER Ca 2+ storage by activating phospholipase C, further increasing the intracellular Ca 2+ concentration

2003, pp