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Nummular eczema Characterized by coin-shaped patches, often with significant barrier disruption and secondary infection

Final thoughts Stopping GHK-Cu typically produces gradual benefit decline over 2-4 months without dramatic rebound effects or rapid reversal to pre-treatment baseline, with 30-40% of long-term users (6+ months treatment) maintaining 50-70% of peak improvements indefinitely while shorter-term users show greater regression toward baseline

10.1016/0092-8674(94)90217-8 56 GullnerG.FodorJ.KirlyL

doi: 10.1186/s12967-023-04116-4 92 GonzlezFSiaCLShepardMKRoteNSMiniumJ