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A dual Annexin V staining/PI flow cytometry assay revealed that AP probe-net significantly enhanced apoptosis in the late stage (Annexin V+/PI + channel), which can be stained by both Annexin V and PI

Covers: chemical development of Melanotan I and II, clinical trials, regulatory complications, the bifurcation into PT-141 and Afamelanotide, underground use

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Rare hypersensitivity reactions may occur in sensitive patients