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Contact a clinician if nausea, constipation, diarrhea, or fatigue keeps returning, worsens, or interferes with fluids and meals

Many people notice subtle changes in their energy or mental clarity after a few weeks of consistent use, but everyones biology is different

Used syringes also lose their silicone coating, increasing friction and making accurate plunger control more difficult

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Importantly, a clinical study has demonstrated that combining radiotherapy with higher doses of the TGF-blocking antibody fresolimumab (10 mg/kg) increases overall survival significantly in metastatic breast cancer patients compared to those undergoing radiotherapy and receiving lower doses of fresolimumab (1 mg/kg) [135]