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Wegovy's cardiovascular risk reduction indication for adults with established cardiovascular disease and either obesity or overweight is the clearest example

The Ozempic, Semaglutide, and GLP-1 Problem For Employers Since the Food and Drug Administration first approved semaglutide (a type of GLP-1 drug) as an injectable weight loss medication in 2021, the demand for brand name versions like Ozempic and Wegovy has skyrocketed

Semaglutide is formulated for once-weekly injection and its seven-day half-life is optimized around this schedule

GLP-1s in general may have the potential to cause certain rare but serious side effects, so the same may apply to retatrutide

For example, reducing left ventricular remodeling is associated with hyperuricemia [290]