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In a mouse study from the University of Utah , animals treated with semaglutide lost about 10% of lean mass overall with skeletal muscle itself decreasing by about 6% , and muscle strength declining disproportionately to size ( University of Utah Health )

While larger and longer-term studies are still needed, this research highlights an exciting shift toward metabolic approaches in joint health and regenerative medicine

In type 2 diabetes, since the sugar is not being used for energy, it stays in your blood

Then it increases to a maintenance dose based on blood sugar response

The 68-week treatment period was followed by a 7-week follow-up period during which patients did not receive Wegovy or placebo