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A role for 12-lipoxygenase in nerve cell death caused by glutathione depletion

infected gastric mucosal phagocytes produce greater amounts of ROS, which is believed to be the major cause of gastric mucosal damage

Preclinical studies have observed its modulatory effects on corticotropin and somatostatin secretion, suggesting its role in neuropeptide feedback loops relevant to stress adaptation and hormonal rhythms

In human SLE, high levels of soluble Fas (sFas) have been measured, and in vitro and in vivo studies in mice have shown that soluble Fas impairs apoptosis induced by Fas ligand [104]