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10.1016/j.abb.2018.03.024 155 NakamuraK.ZhuS.KomatsuK.HattoriM.IwashimaM

The Diabetes Prevention Programme, a large RCT comparing Metformin, ILI and placebo, indicated that after 21 years of follow-up, there was no significant reduction in cancer incidence comparing ILI to placebo (RR 0.96, 95% CI = 0.791.18) [14]

79 Research on antioxidant therapy has generated interest due to its potential in mitigating these conditions

Incretins were identified afterward, and these are intestinal hormones released in response to nutrient ingestion, which then are going to potentially help with this glucose-induced insulin response

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