BAL fluid and intracellular GSH pathways correlate with HAEC T2-associated gene expression To determine whether these in vitro findings were reflected ex vivo, BAL fluid GSSG levels were compared to fresh HAEC expression of T2-related genes from 2 different RNA-Seq databases (SARP3 and IMSA), which were harmonized and merged as outlined in the Methods (Table 3)
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This therapy depends on methionine being administered within 10 hours of poisoning
Oral Glutathione supplements are also available, but absorption can vary because they pass through the digestive system before reaching circulation
Known as the master antioxidant , glutathione is produced naturally in every cell, neutralizing free radicals, supporting detoxification pathways, recycling other antioxidants like vitamin C and E, and maintaining the redox balance that keeps cellular function healthy