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Soft tissue and altered biomechanics in patients with a high BMI can make surgical exposure and component placement more challenging, leading to prolonged operative times

Figure 16: Painting of Professor John C Brown (19382016) by his grandson, Matthew T Kieffer, credit: Kieffer

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Puerarin, isolated from Pueraria lobata (Willd.), protects against hepatotoxicity via specific inhibition of the TGF-1/Smad signaling pathway, thereby leading to anti-fibrotic effect