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Comparison With Other Research Compounds SLU-PP-332 versus mitochondrial and metabolic compounds SLU-PP-332 versus other ERR modulators Consequently, Direct potency comparisons require caution because assay design, receptor expression, reporter system, incubation time, and reference standards can change numerical results
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NNMT as Target (Kraus et al., 2014): NNMT knockdown in white adipose tissue and liver protected against diet-induced obesity by increasing cellular energy expenditure
Research progress Support The animal experiments have achieved remarkable results: In the obese mouse model, after daily subcutaneous injection of AOD 9604 (250 g/kg) for 8 weeks, the body weight of the mice decreased by 12%, the subcutaneous fat mass decreased by 25%, and the weight of epididymal adipose tissue significantly decreased, confirming its effectiveness in fat reduction
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