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GLP-1 Preclinical Study Design and Methods To evaluate systemic toxicity and toxicokinetic characteristics of the GLP-1 RA test article and potential reversibility of any findings, we designed an IND-enabling study that included: a robust dosing schedule of daily oral administration for 28 days

Research labs use it to study multi-hormonal metabolic signaling, energy homeostasis, and the interactions between overlapping incretin pathways

Subcutaneous is the most common method, with most protocols at 250 to 500 mcg per injection

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