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Charlie Seltzer, M.D., an obesity specialist based in Philadelphia

In contrast, Moscat and Diaz-Meco have shown that p62 activates Raptor of mTORC1 leading to the inhibition of autophagy [280]

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p 40% to meet its primary endpoint, addressing a prominent and longstanding therapeutic challenge, since HFpEF constitutes about half of patients with chronic HF and historically has lacked therapies that modify cardiovascular outcomes