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What began as a once-weekly injectable GLP-1 receptor agonist for type 2 diabetes (Ozempic, approved 2017) has evolved into a multi-formulation, multi-indication therapeutic platform with three commercially marketed products: Ozempic (injectable, diabetes + cardiovascular + CKD), Wegovy (injectable, obesity + cardiovascular + MASH), and Rybelsus (oral tablet, diabetes + cardiovascular + obesity)

Once you are ready to proceed, your provider will instruct you on how to use the semaglutide injection, which is usually given once a week as a subcutaneous (under the skin) injection in your abdomen, thigh, or upper arm

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Fasting helps manage eating patterns and supports metabolic health, while semaglutide controls appetite and improves insulin sensitivity

Effectiveness and clinical benefits of new anti-diabetic drugs: A real life experience