Side effects are similar regardless of age: primarily gastrointestinal (nausea, constipation, diarrhea)
While prohibitin is found in mitochondria in most cells, it acts as a receptor on the surface of adipose vasculature, providing a highly specific target for the peptide
Isoform-selective histone deacetylase inhibitors
Shah Z, Kampfrath T, Deiuliis JA, Zhong J, Pineda C, Ying Z, Xu X, Lu B, Moffatt-Bruce S, Durairaj R, Sun Q, Mihai G, Maiseyeu A, Rajagopalan S (2011) Long-term dipeptidyl-peptidase 4 inhibition reduces atherosclerosis and inflammation via effects on monocyte recruitment and chemotaxis
Patients taking degraded products will receive less effective doses