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This evidence-based review provides a comprehensive overview of the GLP-1 receptor agonist class, comparing their mechanisms, indications, pharmacokinetics, and efficacy, and summarizes safety data and guideline recommendations

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Combination therapy Patients with type 2 diabetes mellitus to improve glycemic control in combination with sulfonylurea derivatives (triple combination: metformin + sitagliptin + sulfonylurea derivative) when diet and exercise regimen in combination with two of these three drugs (metformin, sitagliptin or sulfonylurea derivatives) are not lead to adequate glycemic control

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