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Low aqueous solubility, extensive first-pass metabolism, and active efflux sharply curtail systemic exposure to many phytochemicals, inflating required doses and manufacturing costs
Lesniewski, L
These individuals experienced symptoms like nausea, confusion, seizures, and required hospitalization
Today 17, 1147 (2012).CrossRefGoogle ScholarPubMed Wang, Y., Zhao, Q., Han, N., Bai, L., Li, J., Liu, J., Che, E., Hu, L., Zhang, Q., Jiang, T., and Wang, S.: Mesoporous silica nanoparticles in drug delivery and biomedical applications
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