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Testosterone Link: The study found a positive, linear relationship between higher vitamin B12 levels and increased testosterone, suggesting that B12 could help reduce the odds of testosterone deficiency

What Are B12 Shots and Why Do You Need Them

doi: 10.1093/bib/bbae350

Last reviewed: May 30, 2026 Last updated: May 30, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

Injection of local anesthetic into the joint space is sometimes performed to confirm the location of the pain