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Your provider should help you find the dose that works for your body, your goals, and your tolerance

When compounded tirzepatide becomes more accessible or affordable than compounded semaglutide, the practical decision becomes obvious

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You want more flexibility in dosing

In contrast, weight loss magnitude during the pre-landmark period was not significantly associated with post-landmark all-cause mortality ( P = 0.14), the composite cardiovascular endpoint ( P = 0.55), incident cerebrovascular disease ( P = 0.25), incident heart failure ( P = 0.89), or incident valvular or rheumatic heart disease ( P = 0.43) (Fig