The root cause of IBD pathogenesis involves a disruption in the equilibrium between T helper (Th) cells and regulatory T cells, emphasizing the inability of regulatory T cells to function effectively.CD is characterized by inflammation driven by Th1 cells, resulting in an overproduction of IL-12, IL-17, and IL-23 (65)
Lo JO, Schabel MC, Gaffney J, Lewandowski KS, Kroenke CD, Roberts CT Jr., Scottoline BP, Frias AE, Sullivan EL, Roberts VHJ
It also improves overall performance
Continuous stimulation has been theorized to lead to receptor desensitization, whereas intermittent signaling may preserve responsiveness
Following it consistently is what separates people who get results from people who do not