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Starting doses vary by medication: semaglutide (Ozempic/Wegovy) begins at 0.25 mg weekly, dulaglutide (Trulicity) at 0.75 mg weekly, and liraglutide (Victoza/Saxenda) at 0.6 mg daily

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Accordant with the clamp data, Dpp4 hep/ mice had significantly reduced glucose excursion AUC after injection of pyruvate compared with littermate Dpp4 GFP controls (Figure 2A)