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HO-1 is involved in the regulation of macrophage polarization and promotes the M1 state (pro-inflammatory) towards to the M2 state (anti-inflammatory)
In renal failure, perturbed intestinal microorganisms produce several metabolic products that can have an influence on the kidneys, including indoxyl sulfate, trimethylamine N-oxide, phenylacetylglutamine, and p-cresyl sulfate
In principle, these distinct entry points could produce additive AMPK activation, but this dual activation has not been formally studied in humans and warrants physician oversight, particularly regarding blood glucose monitoring
Investigation of the therapeutic effect of Yinchen Wuling powder on Ccl4-induced hepatic fibrosis in rats by 1H Nmr and Ms-based metabolomics analysis
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