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With regard to intestinal proteases, the most important examples in the gut are trypsin and chymotrypsin, which are secreted by the pancreas, and are present in significant quantities throughout the gut lumen

They call for prospective studies with data on reasons for GLP-1 RA use, and use of patient-reported outcome measures to better understand the benefits of GLP-1 RAs versus the impact of chronic cough if it occurs