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Preclinical investigations have examined its activity in tendon, ligament, muscle, bone, gastrointestinal mucosa, and vascular tissue

local use | Both | Local | Systemic | IGF-1 DES may be considered for intramuscular site-specific injection protocols by researchers studying local satellite-cell activation, whereas LR3 is used when prolonged systemic receptor engagement is the research objective [10, 11]

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