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This hypothesis is in agreement with the finding that angiotensin receptor blockers (ARBs) [65,66] and ACE inhibitors [67-69] improve cognitive processing in humans and animal models

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By reducing the oxidative burden on the brainstem and prefrontal cortex, this combination therapy has shown remarkable, life-changing success in improving orthostatic tolerance, reducing tachycardia, and restoring cognitive stamina in severely affected patients

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