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For a fuller treatment of that comparison, see our detailed breakdown of GLP-1 medications versus peptide therapy

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Risks and side effects of phentermine and topiramate include but are not limited to: Anxiety Irritability Constipation Change in taste (possibly metallic taste) Dry mouth Difficulty sleeping Tingling or numbness in the hands & feet Heart palpitations Seizures (rare) Increase in blood pressure Headaches Working with a licensed medical professional can greatly reduce the risks