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doi:10.1038/s41598-024-65310-y Neelakantan H, Hommel JD, Watowich SJ, et al

In REDEFINE 1 , a 68-week, Phase 3a, multicenter, double-blind, placebo- and active-controlled trial, 3,417 adults with overweight or obesity but without diabetes were randomized to CagriSema (cagrilintide 2.4 mg + semaglutide 2.4 mg), semaglutide 2.4 mg, cagrilintide 2.4 mg, or placebo

Thus, vitamin B12 inadequacy is likely to exert the most prominent effects in these sensitive reproductive contexts

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