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GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification

10.1186/1471-2202-7-29 Summary Keywords amyotrophic lateral sclerosis, energy metabolism, medium chain fatty acids, mitochondria, metabolic treatment Citation Tefera TW and Borges K (2017) Metabolic Dysfunctions in Amyotrophic Lateral Sclerosis Pathogenesis and Potential Metabolic Treatments

administered a single oral dose of up to 3 g of GSH to seven healthy subjects and did not observe an increase in blood GSH levels, concluding it is not feasible to increase circulating GSH to a clinically beneficial extent by the oral administration of 3 g of GSH. 22 Yet three studies have evaluated the impact of reduced GSH supplementation combined with oxidative chemotherapeutic agents in patients with various cancers 2325

[33] Recent developments indicate a potential benefit of positron emission tomography (PET) for diagnosis of IPF if suitable radiotracers are applied

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