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Access this article Similar content being viewed by others Data availability Data supporting the findings of this study are available within the article and its supplementary materials will only be made available up on request

In cancers, highly overexpressed arginase is classically associated with an immunosuppressive phenotype by depleting arginine and inhibiting T cell proliferation, activation, and cytotoxicity, leading to impaired immune function, cancer development, and immune evasion [176,177,178]

TCA requires careful patient selection, especially on darker Fitzpatrick types, and should only be performed by a medical provider who can assess the risk of PIH and manage the recovery period

If youre already doing everything else right and still struggling, IV hydration might be the missing piece

The placebo group lost 2.4%