Beyond its local gastrointestinal benefits, research suggests that orally administered BPC-157 can achieve systemic distribution, supporting healing processes throughout the body including joints, muscles, and connective tissues through mechanisms involving growth factor modulation and angiogenesis promotion
however, this study did not assess any mitochondrial function 277
IL-6, which is also increased in obesity (176, 183) can stimulate lipolysis (184) and cause hyperglycemia and hepatic insulin resistance in rats (183) and requires intact JNK signaling in macrophages (183) to promote diet-induced insulin resistance (185)
Websites selling these products claim BPC-157 can be injected or taken orally for bone and joint healing, helping stomach ulcers and increasing athletic performance, and there are plenty of people who share their success stories
Dysbiosis in PCOS is characterized by reduced -diversity, an altered Firmicutes/Bacteroidetes ratio, and depletion of short-chain fatty acid (SCFA)-producing taxa (231)