Among the two polyunsaturated acylcarnitines, octadecadienyl carnitine (C18:2) was found to be decreased in the patients compared to the controls without generating a statistically significant difference (P = 0.113), whereas the concentration of tetradecadienoylcarnitine (C14:2) of the patients and the healthy controls did not differ
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Challenges include batch-to-batch variability, absence of standardized extraction protocols, and inconsistent concentrations of bioactive constituents, all of which complicate compliance with Good Manufacturing Practice (GMP) standards and hinder reproducibility in clinical trials
Several antioxidants (PRDX1,2,5,6