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A mutation in Para-hydroxybenzoate-polyprenyl transferase (COQ2) causes primary coenzyme Q10 deficiency

Research domains include obesity, metabolic regulation, and combination incretin-based therapies

Glucagon-like peptide-1 (GLP-1) is a hormone that triggers the production of insulin

In-depth analyses using metabolomics, epigenetics, and transcriptomics have uncovered GLUT3 as a key determinant in the epigenetic modulation of inflammatory gene profiles

The cytokines released during inflammatory responses may act on the hypothalamus, promoting additional release of CRH and ACTH, which exacerbates HPA axis activation [82]