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Physiology, blood brain barrier

The cardioprotective mechanism proposed involves the enhancement of mitochondrial function, the reduction of oxidative stress, the attenuation of inflammation, and the inhibition of apoptosis (Luna-Marco et al., 2023

Glutathione has also been reported to be a substrate for glutathione peroxidase (GPx) an enzyme which reduces hydrogen peroxide (H 2 O 2 ) in the presence of superoxide dismutase [4]

The primary endpoint was the incidence of MACEs (cardiovascular death, non-fatal myocardial infarction, non-fatal stroke, hospitalization for heart failure)