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Both peptides are considered safe, but Sermorelin is often preferred for age optimization due to its physiological, pulsatile GH release and generally lower risk profile

Factors that affect results: concentration of GHK-Cu (or other copper peptides), complementary ingredients (like hyaluronic acid and antioxidants), sun protection, consistent use, and starting skin condition

V., Macovei, I., Bujor, A., Miron, A., Skalicka-Woniak, K., et al

Three Days Before Treatment Stop Using: Topical prescription products that cause irritation, flaking, or redness

[DOI] [PubMed] [Google Scholar] 58.Marciniak A., Szydlowska I., Brodowska A., Wisniewska B., Nawrocka-Rutkowska J., Starczewski A