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Wang JY, Liu Y, Wang L, Sun

A separate KFF analysis from March about Medicare Part D spending data from the Centers for Medicare & Medicaid Services found that gross Medicare spending on the three newest versions of GLP-1 diabetes medicines (Ozempic, Rybelsus and Mounjaro) that also have been approved for weight loss skyrocketed from $57 million in 2018 to $5.7 billion in 2022

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The foundational obesity finding comes from Kraus and colleagues (Nature, 2014), who showed that knocking down NNMT protected mice against diet-induced obesity establishing NNMT as a metabolic target in the first place