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NICE TA875 specifies that treatment should be reviewed at two years, with continuation only where clinically appropriate within the terms of the appraisal

Gut colonization with methanogenic archaea reduced plasma TMAO levels and attenuated the burden of AS, with decreased area and fat content in the atherosclerotic plaques, in Apo E / mice fed a TMA-supplemented or high choline diet (Ramezani et al., 2018)

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