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Nonetheless, with the exception of certain viral encephalitis and prion disorders [499], such conditions are not fundamentally enigmatic and are less central to current neurodegeneration-focused drug development efforts compared to diseases like AD or frontotemporal lobar degeneration

Additional support for the central role of the brain in OCD comes from a significant body of evidence that OCD is associated with abnormal activity of the neurotransmitters dopamine and serotonin (Koo 2010

Recent studies support that COVID-19 has effects beyond the respiratory tract, with vascular complications arising as relevant factors worsening its prognosis, then making patients with previous vascular disease more prone to severity or fatal outcome