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However, there are side effects patients may experience from the injections

B12 is a water-soluble vitamin, and when administered under medical supervision, its a safe and effective way to improve energy and support metabolism

We order vitamin B12 and folate testing when a person with Down syndrome we are evaluating has symptoms described above, has a lab abnormality for which follow up testing of vitamin B12 and/or folate is indicated, or the person has a condition in which deficiency is common (e.g., celiac disease)