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If a patient cannot sustain that cost, a supervised taper toward the lowest effective dose, or a bridge to a lower-cost agent, protects more of the outcome than an abrupt stop

Temperature excursions, prolonged room-temperature storage beyond 28 days, or exposure to freezing conditions can reduce semaglutide's potency without obvious visual changes

The 3.0 mL dilution gives ~3.33 mg/mL so each dose reads in clear, low single- and double-digit unit marks on a U-100 syringe

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