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Stage 2: Decreased levels of B12 and metabolic abnormalities such as high homocysteine or methylmalonic acid (MMA) levels
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The resulting oxidative stress promotes Drp1-mediated mitochondrial fission, mPTP opening, and membrane depolarization, thereby amplifying apoptotic signaling [52, 138]
they are peptide complexes formed by copper ions combined with tripeptides (GHK-Cu or AHK-Cu)
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